XsFRP5 modulates endodermal organogenesis in Xenopus laevis

TGF-β signals and a prepattern in Xenopus laevis endodermal development

We have analyzed two gene products expressed in the early endoderm of Xenopus laevis: Xlhbox-8, a pancreas-specific transcription factor and intestinal fatty acid binding protein (IFABP), a marker of small intestinal epithelium. Expression of the pancreas marker relies on cell signaling mediated by both the TGF-β and FGF classes of secreted peptide growth factors, whereas, expression of the mor...

Expression of complement components coincides with early patterning and organogenesis in Xenopus laevis.

The complement system is the central component of innate immunity and an important player in the adaptive immunity of vertebrates. We analyzed the expression patterns of several key members of the complement cascade during Xenopus development. We found extensive expression of these molecules already during gastrula/early neurula stage. Remarkably, several genes also showed an organ-specific exp...

Perturbation of Organogenesis by the Herbicide Atrazine in the Amphibian Xenopus laevis

BACKGROUND Exposure to anthropogenic chemicals during development can disrupt the morphogenesis of organ systems. Use of the herbicide atrazine has been debated in recent years because of its implicated, but poorly characterized, effects on vertebrates. Previous studies primarily examined the effects of atrazine exposure during metamorphosis or early developmental stages of amphibians. OBJECT...

ترتیب اعصای جانبی در دم لارو of Xenopus laevis

Cortical grafting in Xenopus laevis.

T H E amphibian egg bears a cortex as the periphery of its cytoplasm. The interpretation by Dalcq & Pasteels (1937) of experiments performed by Pasteels (1938, 1940, 1941), in which fertile eggs of Rana fusca were centrifuged or inverted, led to the suggestion that the cortex possesses properties which control the course of development to some degree. It appeared that the properties of the cort...